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Somatic mutations in chromatin remodeler genes could modify the epigenomic landscape of CLL, but They are really uncommon In this particular malignancy when compared with other lymphoid neoplasms. CHD2 is mutated in 5% of CLL and 7% of MBL.seventy five The histone methyltransferase SETD2 and ARID1A may also be mutated in a little proportion of suff